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		<title>FedericoOShaughn at 18:47, 9 June 2026</title>
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		<summary type="html">&lt;p&gt;&lt;/p&gt;
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				&lt;td colspan=&quot;2&quot; style=&quot;background-color: #fff; color: #202122; text-align: center;&quot;&gt;← Older revision&lt;/td&gt;
				&lt;td colspan=&quot;2&quot; style=&quot;background-color: #fff; color: #202122; text-align: center;&quot;&gt;Revision as of 14:47, 9 June 2026&lt;/td&gt;
				&lt;/tr&gt;&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot; id=&quot;mw-diff-left-l1&quot;&gt;Line 1:&lt;/td&gt;
&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot;&gt;Line 1:&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;−&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&lt;del style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;Some felt previously repressed emotions &lt;/del&gt;and &lt;del style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;appreciated the experience despite its challenge&lt;/del&gt;. &lt;del style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;As intensity plateaued or participants relaxed&lt;/del&gt;, &lt;del style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;positive emotions emerged&lt;/del&gt;. &lt;del style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;I think because of the pre-frame that we had before &lt;/del&gt;and &lt;del style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;we had a conversation yesterday&lt;/del&gt;, &lt;del style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;and it was explained &lt;/del&gt;that &lt;del style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;this is how &lt;/del&gt;the &lt;del style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;process would look like or how it would feel&lt;/del&gt;. &lt;del style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;For some&lt;/del&gt;, &lt;del style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;the experience of loss of control&lt;/del&gt;, &lt;del style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;changing boundaries, or complete dissociation was anxiety provoking, others found these sensations pleasant&lt;/del&gt;. &lt;del style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;A few participants described &lt;/del&gt;the &lt;del style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;sensations as if their mind, spirit or soul was separating from their bod&amp;lt;br&amp;gt;&amp;lt;br&amp;gt;&quot;Our results revealed that when &lt;/del&gt;a &lt;del style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;volunteer was on DMT there was a marked dysregulation of some of the brain rhythms that would ordinarily be dominant&lt;/del&gt;. The &lt;del style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;brain switched in its mode &lt;/del&gt;of &lt;del style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;functioning to something altogether more anarchi&amp;lt;br&amp;gt;&amp;lt;br&amp;gt; In contrast to most serotonergic psychedelics however&lt;/del&gt;, &lt;del style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;it has been said that it is unclear that &lt;/del&gt;the &lt;del style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;hallucinogenic effects &lt;/del&gt;of &lt;del style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;[https://coopspace&lt;/del&gt;.&lt;del style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;online/index&lt;/del&gt;.&lt;del style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;php?title=User:AliCadman7009 5-MeO-DMT] are principally mediated by activation of the serotonin 5-HT2A recepto&lt;/del&gt;&amp;lt;br&amp;gt;&lt;del style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;&amp;lt;br&amp;gt; DMT is a potent psychedelic found naturally in certain plants &lt;/del&gt;and &lt;del style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;animals&lt;/del&gt;. &lt;del style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;It occurs in trace amounts in &lt;/del&gt;the &lt;del style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;human body &lt;/del&gt;and &lt;del style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;is &lt;/del&gt;the &lt;del style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;major psychoactive compound in ayahuasca – the psychedelic brew prepared from vines &lt;/del&gt;and &lt;del style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;leaves &lt;/del&gt;and &lt;del style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;used in ceremonies in south &lt;/del&gt;and &lt;del style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;central Americ&amp;lt;br&amp;gt;&amp;lt;br&amp;gt;&amp;lt;br&amp;gt;PVT &lt;/del&gt;and &lt;del style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;DSST were included in order to capture potential negative effects on cognition &lt;/del&gt;and &lt;del style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;did not show any impairment &lt;/del&gt;of &lt;del style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;cognitive function&lt;/del&gt;. &lt;del style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;Mean (SE) MADRS ratings in the Phase 1 and Phase 2 parts &lt;/del&gt;of the &lt;del style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;study are shown &lt;/del&gt;in &lt;del style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;Figure 3&lt;/del&gt;. &lt;del style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;In the Phase 2 part, applying the IDR, 7 out of 8 patients achieved &lt;/del&gt;a &lt;del style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;PE&lt;/del&gt;, &lt;del style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;whereby 6 patients achieved a PE after the second administration (6 mg + 12 mg), and one patient achieved a PE after the third administration (6 mg + 12 mg + 18 mg&lt;/del&gt;&amp;lt;br&amp;gt;&lt;del style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;&amp;lt;br&amp;gt;&amp;lt;br&amp;gt;He told Belichick that he didn�t want to waste his time and left. On the day Gallery knew his NFL career was over&lt;/del&gt;, &lt;del style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;he walked into New England head coach Bill Belichick�s office and thanked him &lt;/del&gt;for the &lt;del style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;opportunity&lt;/del&gt;. &lt;del style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;As time went on&lt;/del&gt;, &lt;del style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;Gallery would find himself easily triggered. �And what did we do after games when the times were rough? And one day&lt;/del&gt;, &lt;del style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;he came home &lt;/del&gt;to &lt;del style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;a note on his door imploring him and his family to move&lt;/del&gt;. &lt;del style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;�I was very close a couple &lt;/del&gt;of &lt;del style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;times,� he answere&lt;/del&gt;&amp;lt;br&amp;gt;&lt;del style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;&amp;lt;br&amp;gt;&amp;lt;br&amp;gt;Coefficients of GLM &lt;/del&gt;of &lt;del style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;theta-SG modulation, estimated using &lt;/del&gt;the &lt;del style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;injected drug (top) and taking &lt;/del&gt;the &lt;del style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;dose into account (bottom, right) for IP (light blue) and ICV (magenta) injections&lt;/del&gt;. &lt;del style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;To address &lt;/del&gt;the &lt;del style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;decrease in theta power caused by the drug we integrated theta amplitude into our matching analysis, enabling us to examine any additional effects &lt;/del&gt;on &lt;del style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;modulation beyond &lt;/del&gt;this &lt;del style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;reduction alone. To investigate theta-nested gamma oscillations, &lt;/del&gt;we &lt;del style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;ran a matching analysis &lt;/del&gt;to &lt;del style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;determine whether any effects on gamma oscillations were in addition to what would be expected &lt;/del&gt;from &lt;del style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;theta power reductions and speed changes&lt;/del&gt;. &lt;del style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;To further investigate the effects of the drug on the power of delta &lt;/del&gt;and &lt;del style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;theta&lt;/del&gt;, &lt;del style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;we used a generalised linear model (GLM) approach. To achieve this&lt;/del&gt;, &lt;del style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;we randomly selected theta cycles from the post&lt;/del&gt;-&lt;del style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;injection period and paired them with cycles from &lt;/del&gt;the &lt;del style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;baseline period (without repetition) that had similar speed and theta powe&amp;lt;br&amp;gt;&amp;lt;br&amp;gt;&amp;lt;br&amp;gt;If &lt;/del&gt;the &lt;del style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;brain is like a biological computer—a dominant assumption of cognitive neuroscience—then maybe researchers can compare how LLMs process information and test for indicators of consciousness&lt;/del&gt;. &lt;del style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;&quot;People have focused a lot on where consciousness is in &lt;/del&gt;the &lt;del style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;brain &lt;/del&gt;and &lt;del style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;perhaps less so on what it’s for&lt;/del&gt;,&lt;del style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;&quot; Seth says. Sometime in the 20th century&lt;/del&gt;, &lt;del style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;though&lt;/del&gt;, &lt;del style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;scientists stopped doing so for animals&lt;/del&gt;. &lt;del style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;For everyone else, we must rely on behavioral cues &lt;/del&gt;and &lt;del style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;trust they are not a &quot;philosophical zombie&lt;/del&gt;,&lt;del style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;&quot; &lt;/del&gt;with &lt;del style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;all the outward signs of consciousness but without any of the internal experience&lt;/del&gt;.&amp;lt;br&amp;gt; &lt;del style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;MeO&lt;/del&gt;-&lt;del style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;DMT effects on waking behaviour &amp;lt;br&amp;gt;This time, during Gallery�s 5-MeO&lt;/del&gt;-&lt;del style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;DMT session, he hallucinated that he killed himself &lt;/del&gt;on &lt;del style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;5-meo-dmt his motorcycle&lt;/del&gt;. &lt;del style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;But over time, normal life began getting under his skin. That night, &lt;/del&gt;as &lt;del style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;Gallery began to feel better&lt;/del&gt;, &lt;del style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;he started journaling, and gradually his experience came back &lt;/del&gt;to &lt;del style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;him&lt;/del&gt;. &lt;del style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;This was one &lt;/del&gt;of the &lt;del style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;reasons the FDA ended federal research &lt;/del&gt;on the &lt;del style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;drug in 199&amp;lt;br&amp;gt;&amp;lt;br&amp;gt;&amp;lt;br&amp;gt;Hordubei sells amanita to customers online and takes it himself, but unlike Soloshenko&lt;/del&gt;, &lt;del style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;he doesn’t credit the mushroom with any major life changes or shifts &lt;/del&gt;in &lt;del style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;his mental health&lt;/del&gt;. &lt;del style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;Another GABA mimic &lt;/del&gt;is &lt;del style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;alcohol, and users have described the effects of medium-to-high doses of amanita as similar to being inebriated. When eaten &lt;/del&gt;raw&lt;del style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;, large doses of amanita trigger a dreamlike, potentially frightening experience &lt;/del&gt;that &lt;del style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;lasts hours &lt;/del&gt;and &lt;del style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;can, on rare occasions, be deadl&lt;/del&gt;&amp;lt;br&amp;gt;&amp;lt;br&amp;gt;&lt;del style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;&amp;lt;br&amp;gt;Faced with an existential unknown, the public is turning to the field of consciousness science for answers. Sometimes these artificial-intelligence models claim outright to be sentient. We’ve built talking machines able to imitate consciousness so well that we can’t always tell the differenc&lt;/del&gt;&lt;/div&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;+&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;&amp;lt;br&amp;gt;&amp;lt;br&amp;gt;&amp;lt;br&amp;gt;These could include affectionateness palpitations &lt;/ins&gt;and &lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;grave interactions with former medications&lt;/ins&gt;. &lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;In about cases, these pills fundament be contaminated&lt;/ins&gt;, &lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;sitting additional risks. 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&lt;/table&gt;</summary>
		<author><name>FedericoOShaughn</name></author>
	</entry>
	<entry>
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		<title>MackRichie627: Created page with &quot;Some felt previously repressed emotions and appreciated the experience despite its challenge. As intensity plateaued or participants relaxed, positive emotions emerged. I think because of the pre-frame that we had before and we had a conversation yesterday, and it was explained that this is how the process would look like or how it would feel. For some, the experience of loss of control, changing boundaries, or complete dissociation was anxiety provoking, others found th...&quot;</title>
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		<updated>2026-05-17T02:24:20Z</updated>

		<summary type="html">&lt;p&gt;Created page with &amp;quot;Some felt previously repressed emotions and appreciated the experience despite its challenge. As intensity plateaued or participants relaxed, positive emotions emerged. I think because of the pre-frame that we had before and we had a conversation yesterday, and it was explained that this is how the process would look like or how it would feel. For some, the experience of loss of control, changing boundaries, or complete dissociation was anxiety provoking, others found th...&amp;quot;&lt;/p&gt;
&lt;p&gt;&lt;b&gt;New page&lt;/b&gt;&lt;/p&gt;&lt;div&gt;Some felt previously repressed emotions and appreciated the experience despite its challenge. As intensity plateaued or participants relaxed, positive emotions emerged. I think because of the pre-frame that we had before and we had a conversation yesterday, and it was explained that this is how the process would look like or how it would feel. For some, the experience of loss of control, changing boundaries, or complete dissociation was anxiety provoking, others found these sensations pleasant. A few participants described the sensations as if their mind, spirit or soul was separating from their bod&amp;lt;br&amp;gt;&amp;lt;br&amp;gt;&amp;quot;Our results revealed that when a volunteer was on DMT there was a marked dysregulation of some of the brain rhythms that would ordinarily be dominant. The brain switched in its mode of functioning to something altogether more anarchi&amp;lt;br&amp;gt;&amp;lt;br&amp;gt; In contrast to most serotonergic psychedelics however, it has been said that it is unclear that the hallucinogenic effects of [https://coopspace.online/index.php?title=User:AliCadman7009 5-MeO-DMT] are principally mediated by activation of the serotonin 5-HT2A recepto&amp;lt;br&amp;gt;&amp;lt;br&amp;gt; DMT is a potent psychedelic found naturally in certain plants and animals. It occurs in trace amounts in the human body and is the major psychoactive compound in ayahuasca – the psychedelic brew prepared from vines and leaves and used in ceremonies in south and central Americ&amp;lt;br&amp;gt;&amp;lt;br&amp;gt;&amp;lt;br&amp;gt;PVT and DSST were included in order to capture potential negative effects on cognition and did not show any impairment of cognitive function. Mean (SE) MADRS ratings in the Phase 1 and Phase 2 parts of the study are shown in Figure 3. In the Phase 2 part, applying the IDR, 7 out of 8 patients achieved a PE, whereby 6 patients achieved a PE after the second administration (6 mg + 12 mg), and one patient achieved a PE after the third administration (6 mg + 12 mg + 18 mg&amp;lt;br&amp;gt;&amp;lt;br&amp;gt;&amp;lt;br&amp;gt;He told Belichick that he didn�t want to waste his time and left. On the day Gallery knew his NFL career was over, he walked into New England head coach Bill Belichick�s office and thanked him for the opportunity. As time went on, Gallery would find himself easily triggered. �And what did we do after games when the times were rough? And one day, he came home to a note on his door imploring him and his family to move. �I was very close a couple of times,� he answere&amp;lt;br&amp;gt;&amp;lt;br&amp;gt;&amp;lt;br&amp;gt;Coefficients of GLM of theta-SG modulation, estimated using the injected drug (top) and taking the dose into account (bottom, right) for IP (light blue) and ICV (magenta) injections. To address the decrease in theta power caused by the drug we integrated theta amplitude into our matching analysis, enabling us to examine any additional effects on modulation beyond this reduction alone. To investigate theta-nested gamma oscillations, we ran a matching analysis to determine whether any effects on gamma oscillations were in addition to what would be expected from theta power reductions and speed changes. To further investigate the effects of the drug on the power of delta and theta, we used a generalised linear model (GLM) approach. To achieve this, we randomly selected theta cycles from the post-injection period and paired them with cycles from the baseline period (without repetition) that had similar speed and theta powe&amp;lt;br&amp;gt;&amp;lt;br&amp;gt;&amp;lt;br&amp;gt;If the brain is like a biological computer—a dominant assumption of cognitive neuroscience—then maybe researchers can compare how LLMs process information and test for indicators of consciousness. &amp;quot;People have focused a lot on where consciousness is in the brain and perhaps less so on what it’s for,&amp;quot; Seth says. Sometime in the 20th century, though, scientists stopped doing so for animals. For everyone else, we must rely on behavioral cues and trust they are not a &amp;quot;philosophical zombie,&amp;quot; with all the outward signs of consciousness but without any of the internal experience.&amp;lt;br&amp;gt; MeO-DMT effects on waking behaviour &amp;lt;br&amp;gt;This time, during Gallery�s 5-MeO-DMT session, he hallucinated that he killed himself on 5-meo-dmt his motorcycle. But over time, normal life began getting under his skin. That night, as Gallery began to feel better, he started journaling, and gradually his experience came back to him. This was one of the reasons the FDA ended federal research on the drug in 199&amp;lt;br&amp;gt;&amp;lt;br&amp;gt;&amp;lt;br&amp;gt;Hordubei sells amanita to customers online and takes it himself, but unlike Soloshenko, he doesn’t credit the mushroom with any major life changes or shifts in his mental health. Another GABA mimic is alcohol, and users have described the effects of medium-to-high doses of amanita as similar to being inebriated. When eaten raw, large doses of amanita trigger a dreamlike, potentially frightening experience that lasts hours and can, on rare occasions, be deadl&amp;lt;br&amp;gt;&amp;lt;br&amp;gt;&amp;lt;br&amp;gt;Faced with an existential unknown, the public is turning to the field of consciousness science for answers. Sometimes these artificial-intelligence models claim outright to be sentient. We’ve built talking machines able to imitate consciousness so well that we can’t always tell the differenc&lt;/div&gt;</summary>
		<author><name>MackRichie627</name></author>
	</entry>
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